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 Acebutolol
Product Name Acebutolol
Company Catalog
CAS No. 37517-30-9
Specifications BP/USP/EP
Packaging 1.0kgs/Al- Bottle 2.0kgs/Al- Bottle 5.0 kgs/Al-Bottle 25.0 kgs/drum
Product Description

Introduction

Acebutolol ( CAS:37517-30-9 ) is a cardioselective beta blocker with ISA (intrinsic sympathomimetic activity; see article on pindolol). It is therefore more suitable than non cardioselective beta blockers, if a patient with asthma or chronic obstructive pulmonary disease (COPD) needs treatment with a beta blocker.

Product name:Acebutolol

CAS NO:37517-30-9

MF: C18H28N2O4

Purity:99%
Function

Suitable for sinus tachycardia, atrial or Ventricular Premature Beats and Atrial Fibrillation, atrial flutter, etc. are also used for angina, high blood pressure. 

Application

Applicable to all types of high blood pressure, antihypertensive effect is similar to a give Ringling or metoprolol, heart rate without slowing down, and are not subject to the effects of age, race, or renal insufficiency. For the treatment of angina pectoris, in reducing the frequency of angina attacks, reduce the amount of nitroglycerine, increase exercise tolerance and improving the degree of myocardial ischemia, and nifedipine is as effective. Can also be used in the treatment of ventricular arrhythmia, this product was estimated to have 40% in patients with ventricular premature beats by 75% and kuinidingyi tolerance.

Specification

Test  Item

Analysis  Specification

Result

Description

White crystalline powder

Conforms

Melting range

129°C~132°C

130.8°C-131°C

Loss on drying

≤0.5%

0.20 %

Specific rotation

-58°~-62°(C=1,in CH3OH)

-61.05°

Sulphated ash

≤0.1%

0.08 %

Heavy metals

≤10ppm

Conforms

Chlorides

≤0.02%

Conforms

Sulfates

≤0.02%

Conforms

Fluorine

14.7%~17.9%

15.2%

Residual solvent

Methanol ≤0.2%

Isopropanol ≤0.2%

Ethyl acetate≤0.2%

Chloroform ≤0.2%

0.0%

0.0%

0.0%

0.0%

Related substances

(HPLC)

Single impurity ≤0.2%

Total impurities ≤0.5%

0.05%

0.08%

Assay

≥99.5%

99.92%

Conclusion

Accordance with the reference

 

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