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Lynestrenol cas no 52-76-6
Product Name Lynestrenol cas no 52-76-6
Company Catalog
CAS No. 52-76-6
Specifications BP/USP/EP
Packaging 1.0kgs/Al- Bottle 2.0kgs/Al- Bottle 5.0 kgs/Al-Bottle 25.0 kgs/drum
Product Description

Pharmaceutical intermediate Lynestrenol cas no 52-76-6

Introduction

Lynestrenol is a progestogen horne. It is a synthetic orally-available progestagen associated with numerous effects of the natural progesterone hoone. Lynestrenol has a strong progestational effect on the uterine endometrium (transforming proliferative endometrium into secretory one), inhibits secretion of gonadotropin, suppresses maturation of follicles in the ovaries and ovulation, reduces menstrual bleeding. This synthetic gestagen is associated with minimal estrogenic, androgenic and anabolic effects. Lynestrenol is used in treatment of hoonal disorders and diseases caused by insufficient secretion of the natural progesterone, except in case of risky pregnancies and prevention of miscarriage, since it is not efficient enough in this indication.
Pharmacology
After oral administration lynestrenol is quickly resorbed and converted into pharmacologically active norethisterone, through which it demonstrates the main biological effects. The peak blood are reached within 2–4 hours after oral administration, 97% of the administered dose being bound to plasma proteins. Lynestrenol and its metabolites are predominantly excreted in the urine, less through feces, active metabolite norethisterone elimination halftime being 16-17 h.
Product name Good Hot sale Lynestrenol 
CAS No.: 52-76-6
MF. C20H28O
MW. 284.44
Assay  ≥99.0%
Appearance White or white crystalline powder

Function

orethindrone for 19 - methyl test class oral progesterone effectively, with mild androgen and estrogen activity. Ovulation resistant; Increase the cervical mucus viscosity, bad sperm upward into the uterine cavity; Influence of endometrium, not con.

1-Progesterone also known as P4 is a C-21 steroid homone involved in the female menstrual cycle, pregnancy(support gestation) and embryogenesis of humans and other species;

2-Progesterone belongs to a class of hormones called progestogens, that is major naturally occurring human progestogen;

3-Used in the treatment of advanced breast cancer, endometrial adenocarcinoma and kidney cancer;

4-Used in dysmenorrheal, functional amenorrhea, dysfunctional uterine bleeding, threatened abortion, etc.

5- Progesterone is one of the strongest activity progestogens. It can be used to cure association dues, Prostatic hyperplasia, renal colic.

Application

1-Induces maturation and secretory activity of the uterine endothelium, suppresses ovulation. It is implicated in the etiology of breast cancer;

2-Progesterone is sensitive to light. It is used in biochemical research;

3-Progesterone drugs, used in curing inertia abortion, threatened abortion, dysmenorrheal, amenorrhoea etc.

Specification

 

Item

Specification

Result

Appearance

White crystalline powder

Complies

Related substance (HPLC)

Total impurity 0.5%

Max single impurity 0.1%

0.2%

0.06%

Odor

Characteristic

Complies

Assay

99%

99.8%

Sieve analysis

100% pass 80 mesh

Complies

Loss on Drying

Residue on Ignition

≤1.0%

≤1.0%

0.12%

0.09%

Heavy Metal

<10ppm

Complies

As

<0.1ppm

0.05ppm

Pb

<0.1ppm

0.05ppm

Cd

<0.1ppm

0.05ppm

Residual Solvents

<100ppm

Complies

Residual Pesticide

Negative

Complies

Microbiology

 

 

Total Plate Count

<1000cfu/g

Complies

Yeast & Mold

<100cfu/g

Complies

E.Coli

Negative

Complies

Salmonella

Negative

Complies


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